Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 14/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536567 | 0.83 | DUT (0.47) | DUTNAMPTBRD4ROCK2 | |
| SCHEMBL21536723 | 0.76 | DUT (0.47) | DUTNAMPTALDH1A1BRD4NPC1 | |
| SCHEMBL21536722 | 0.75 | DUT (0.49) | DUTNAMPTALDH1A1BRD4NPC1 | |
| SCHEMBL24153844 | 0.75 | DUT (0.41) | DUTALDH1A1NPC1ROCK2 | |
| SCHEMBL21536673 | 0.75 | DUT (0.46) | DUTNAMPTALDH1A1 | |
| SCHEMBL21536060 | 0.73 | DUT (0.46) | DUTNAMPTALDH1A1BRD4ROCK2 | |
| SCHEMBL21536677 | 0.72 | DUT (0.46) | DUTNAMPTALDH1A1BRD4ROCK2 | |
| SCHEMBL21536563 | 0.72 | DUT (0.50) | DUTNAMPTALDH1A1 | |
| SCHEMBL21536061 | 0.71 | DUT (0.41) | DUT | |
| SCHEMBL21536576 | 0.70 | DUT (0.49) | DUTNAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168059-B2 | Amino sulfonyl compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168059-B2 | Amino sulfonyl compounds | DPYD, DNPEP, DUT | DUT 3/4885NAMPT 911/4885ALDH1A1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.