Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536604 | 0.83 | DUT (0.45) | DUTALDH1A1MAPTL3MBTL1ROCK2 | |
| SCHEMBL20351362 | 0.80 | DUT (0.64) | DUTHCRTR1HCRTR2 | |
| SCHEMBL21536601 | 0.78 | DUT (0.45) | DUTALDH1A1MAPTROCK2 | |
| SCHEMBL23996252 | 0.75 | DUT (0.45) | DUTALDH1A1ROCK2NPC1 | |
| SCHEMBL21536596 | 0.73 | DUT (0.43) | DUTALDH1A1ROCK2NPC1 | |
| SCHEMBL21536718 | 0.73 | DUT (0.43) | DUTALDH1A1ROCK2NPC1 | |
| SCHEMBL21536714 | 0.72 | DUT (0.49) | DUTALDH1A1MAPT | |
| SCHEMBL21536566 | 0.72 | DUT (0.45) | DUTALDH1A1MAPTL3MBTL1ROCK2 | |
| SCHEMBL21536677 | 0.71 | DUT (0.46) | DUTALDH1A1MAPTROCK2 | |
| SCHEMBL21536736 | 0.71 | DUT (0.44) | DUTL3MBTL1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263205-A1 | COMBINATION THERAPY WITH DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-12-30 | — | — | WO | disclosed |