Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899162 | 0.76 | HSD17B10 (0.47) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL8809819 | 0.76 | HSD17B10 (0.47) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL29448834 | 0.76 | TSHR (0.45) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL4429 | 0.76 | HSD17B10 (0.47) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL14572994 | 0.76 | TSHR (0.41) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL4970711 | 0.74 | BRD4 (0.42) | TSHRMAOBCYP19A1 | |
| SCHEMBL9177187 | 0.73 | NISCH (0.58) | TSHRMAOBKDM4EADORA3AR | |
| SCHEMBL4969411 | 0.73 | MAOB (0.50) | MAOBCYP19A1HSD17B10 | |
| SCHEMBL2362658 | 0.73 | MAOB (0.54) | MAOBCYP19A1 | |
| SCHEMBL4970322 | 0.70 | ATM (0.38) | TSHRMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | claimed |
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| EP-2069513-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | California Institute of Technology (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090061471-A1 | Methods and systems for selective fluorination of organic molecules | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2009-03-05 | — | — | US | disclosed |
| WO-2008016709-A9 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INST OF TECHN (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008016709-A2 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | WO | disclosed |