SCHEMBL4429

SCHEMBL4429

O=C1NCC(c2ccccc2)O1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.45
MAOB P27338 6/20 0.44
CYP19A1 P11511 3/20 0.44
AR P10275 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CA2 P00918 1/20 0.44
PKM P14618 1/20 0.41
MAOA P21397 1/20 0.38
PSMB5 P28074 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8809819 1.00 HSD17B10 (0.47) HSD17B10USP2ALDH1A1HPGDLMNA
SCHEMBL2899162 1.00 HSD17B10 (0.47) HSD17B10USP2ALDH1A1HPGDLMNA
SCHEMBL13547538 0.82 DDB1 (0.39) HSD17B10USP2ALDH1A1HPGDLMNA
SCHEMBL9243943 0.81 MAOB (0.44) LMNAMAOBPKMMAOA
SCHEMBL9109652 0.81 MAOB (0.44) LMNAMAOBPKMMAOA
SCHEMBL2722147 0.81 SLC6A3 (0.46)
SCHEMBL2901706 0.81 SLC6A3 (0.46)
SCHEMBL5021254 0.81 MAOB (0.44) MAOB
SCHEMBL20840267 0.81 DDB1 (0.40) HSD17B10USP2ALDH1A1HPGDMAOB
SCHEMBL8234131 0.81 USP2 (0.35) HSD17B10USP2ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110257033-B Water-based cleaning solution and preparation method and application thereof 中国海洋石油集团有限公司 2021-09-10 CN claimed
CN-110257033-A A kind of water-base cleaning liquid and its preparation method and application 中国海洋石油集团有限公司 2019-09-20 CN claimed
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-11-12 US claimed
WO-2009056993-A2 A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-05-07 WO claimed
WO-2025149498-A1 BENZYLPIPERIDINE DERIVATIVES AS TRP4 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ASTRAZENECA AB (SE) 2025-07-17 WO disclosed
US-20250129067-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF PROGENTOS THERAPEUTICS, INC. (US) 2025-04-24 US disclosed
CN-119060991-A Reaction process for preparing (S) -4-phenyl-2-oxazolidinone with high chiral purity and biocatalyst 宁波酶赛生物工程有限公司 2024-12-03 CN disclosed
EP-4430047-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF Progentos Therapeutics, Inc. (US) 2024-09-18 EP disclosed
US-20240294482-A1 METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR INNER MONGOLIA UNIVERSITY OF TECHNOLOGY (CN) 2024-09-05 US disclosed
CN-118475580-A Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof 普罗根托斯治疗公司 2024-08-09 CN disclosed
CN-118207195-A Enzymatic preparation of (S) -4-phenyl-2-oxazolidinone and (S) -oxirane 宁波酶赛生物工程有限公司 2024-06-18 CN disclosed
CN-115043810-B Method for preparing chiral hydrocarbon bond oxidation product by non-metal catalyzed asymmetric hydrocarbon bond oxidation 浙江大学 2024-04-19 CN disclosed
EP-0037141-A1 Purification of cyanuric acid FMC Corporation (US) 1981-10-07 EP disclosed
US-4282359-A MECHANICAL SEPARATION FROM HEATED SLURRY CONTAINING UREA ANOR BIURET FMC CORPORATION (US) 1981-08-04 US disclosed
US-4275202-A Production of a purified cyanuric acid dihydrate FMC CORPORATION (US) 1981-06-23 US disclosed
US-4232162-A P-Substituted N,N'-bis-(3-oxazolidinyl-2-one)phosphoramides and process for the preparation thereof ANTIBIOTICS, S.A. (ES) 1980-11-04 US disclosed
US-4172198-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-10-23 US disclosed
US-4009039-A Heat developable light-sensitive oxazoline containing element FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed
US-4007168-A Process for preparing penicillins derivatives PALOMO COLL A L 1977-02-08 US disclosed
US-3947465-A 3-Alkylsilyl-2-oxazolidonone compounds and synthesis thereof PALOMO COLL A L 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 HSD17B10 146/4885USP2 2859/4885ALDH1A1 1460/4885
US-20240294482-A1 METHOD FOR CATALYTICALLY ACTIVATING CARBON DIOXIDE AS CARBONYLATION REAGENT WITH INORGANIC SULFUR TST, CBR3, SMOX HSD17B10 1617/4885USP2 914/4885ALDH1A1 639/4885
US-20250129067-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF PDGFRB, PDGFRA, PDGFA HSD17B10 4245/4885USP2 2259/4885ALDH1A1 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.