Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362658 | 0.88 | MAOB (0.54) | MAOBALDH1A1MAPTNISCHCYP19A1 | |
| SCHEMBL30991550 | 0.82 | MAOB (0.50) | MAOBHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30317182 | 0.82 | NISCH (0.40) | MAOBCYP1A2KMT2AHSD17B10GAA | |
| SCHEMBL4971664 | 0.82 | ADAMTS5 (0.42) | MAOBKMT2AHSD17B10SMN1; SMN2GAA | |
| SCHEMBL6981999 | 0.81 | ABCG2 (0.56) | MAOBCYP3A4HPGDKMT2AHSD17B10 | |
| SCHEMBL9177187 | 0.80 | NISCH (0.58) | MAOBCYP3A4HPGDKMT2AHSD17B10 | |
| SCHEMBL22570946 | 0.78 | BRD4 (0.45) | MAOBCYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL30991556 | 0.77 | MAOB (0.41) | MAOBCYP1A2HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL22791631 | 0.76 | CREBBP (0.58) | CYP1A2CYP3A4CYP2C9HPGDCYP2C19 | |
| SCHEMBL22791978 | 0.76 | CREBBP (0.58) | CYP1A2CYP3A4CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985297-A1 | CARBOXYLIC ACID COMPOUND AND USE THEREOF | Japan Tobacco, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | JAPAN TOBACCO INC. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197512-A1 | Carboxylic Acid Compounds and Use Thereof | GLS, SLC10A1, SOAT1 | MAOB 2759/4885CYP1A2 1140/4885CYP3A4 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.