Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726961 | 0.69 | PDE10A (0.50) | PDE10A | |
| SCHEMBL23997406 | 0.68 | P2RX7 (0.39) | — | |
| SCHEMBL29274137 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL30761104 | 0.67 | PDE10A (0.40) | PDE10A | |
| SCHEMBL23997250 | 0.66 | GBA1 (0.36) | — | |
| SCHEMBL14726808 | 0.65 | PDE10A (0.49) | PDE10A | |
| SCHEMBL30608276 | 0.65 | PDE10A (0.49) | PDE10A | |
| SCHEMBL17449566 | 0.65 | PDE10A (0.49) | PDE10A | |
| SCHEMBL20198839 | 0.65 | PDE10A (0.49) | PDE10A | |
| SCHEMBL30608275 | 0.65 | PDE10A (0.49) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |