SCHEMBL239979

SCHEMBL239979

C1=Cc2c3c(ccc2=N1)=c1ccccc1=N3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29246278 0.89
SCHEMBL8880037 0.85
Benzothiophene SCHEMBL28770302 0.84
SCHEMBL191345 0.76 ALDH1A1 (0.30)
SCHEMBL4515091 0.71
SCHEMBL2047647 0.69
SCHEMBL9044942 0.68 NPSR1 (0.31)
SCHEMBL29263176 0.68
SCHEMBL4488759 0.67
SCHEMBL29229513 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047753-A Pyrrolecarboxyl carbazole derivatives and their use in phosphorescent materials 三峡大学 2024-05-17 CN claimed
US-20230416782-A1 ENHANCED NANOPARTICLE DELIVERY SYSTEMS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-12-28 US claimed
EP-4259207-A1 ENHANCED NANOPARTICLE DELIVERY SYSTEMS Children's Hospital Medical Center (US) 2023-10-18 EP claimed
US-20220202950-A1 COMPOSITIONS COMPRISING BACTERIALLY DERIVED INTACT MINICELLS FOR THERANOSTIC APPLICATIONS ENGENEIC MOLECULAR DELIVERY PTY LTD (AU) 2022-06-30 US claimed
WO-2022125784-A1 ENHANCED NANOPARTICLE DELIVERY SYSTEMS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2022-06-16 WO claimed
CN-113912621-A Containing SO2Spiro pyrrolocarbazoles and application thereof 北京云基科技有限公司 2022-01-11 CN claimed
CN-113880861-A Containing SO2Spiro pyrrolocarbazoles compounds and application thereof 北京云基科技有限公司 2022-01-04 CN claimed
WO-2020222161-A1 COMPOSITIONS COMPRISING BACTERIALLY DERIVED INTACT MINICELLS FOR THERANOSTIC APPLICATIONS ENGENEIC MOLECULAR DELIVERY PTY LTD (AU) 2020-11-05 WO claimed
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 EP claimed
US-9650614-B2 Anaplastic lymphoma kinase (ALK) as oncoantigen for lymphoma vaccination CHIARLE, Roberto (IT) 2017-05-16 US claimed
US-5705511-A ENZYME INHIBITORS, ANTIINFLAMMATORY, TROPHIC FACTOR, ANTICANCER CELL GROWTH CEPHALON, INC. (US) 1998-01-06 US claimed
CN-1035878-C Indolopyrrolocarbazole derivatives BANYU PHARMA CO LTD (JP) 1997-09-17 CN claimed
EP-0785938-A1 FUSED PYRROLOCARBAZOLES CEPHALON, INC. (US) 1997-07-30 EP claimed
EP-0768311-A1 PYRROLOCARBAZOLE DERIVATIVES KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-04-16 EP claimed
US-5594009-A KINASE INHIBITORS, TROPHIC FACTOR-INDUCED ACTIVITY ENHANCEMENT, CELL SURVIVAL CEPHALON, INC. (US) 1997-01-14 US claimed
US-5591855-A KINASE INHIBITORS, TROPHIC FACTOR-INDUCED ACTIVITY ENHANCEMENT, CELL SURVIVAL CEPHALON, INC. (US) 1997-01-07 US claimed
WO-1996011933-A1 FUSED PYRROLOCARBAZOLES CEPHALON, INC. (US) 1996-04-25 WO claimed
US-5475110-A Treating nervous system disorders and inflammation, inhibiting protein and tyrosine kinases, inhibiting cell growth CEPHALON, INC. (US) 1995-12-12 US claimed
CN-1075482-A Indoles and pyrrolo carbazole derivatives BANYU PHARMA CO LTD (JP) 1993-08-25 CN claimed
EP-0362695-B1 PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS GÖDECKE AKTIENGESELLSCHAFT (DE) 1991-04-03 EP claimed