Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246278 | 0.64 | — | — | |
| SCHEMBL11985519 | 0.54 | — | — | |
| SCHEMBL10975623 | 0.54 | ALDH1A1 (0.42) | NPSR1 | |
| SCHEMBL576916 | 0.53 | ALDH1A1 (0.47) | — | |
| SCHEMBL12997586 | 0.49 | ALDH1A1 (0.47) | — | |
| Biphenyl SCHEMBL20530383 | 0.48 | ALDH1A1 (0.64) | — | |
| Biphenyl SCHEMBL27604303 | 0.48 | ALDH1A1 (0.64) | — | |
| Biphenyl SCHEMBL28489818 | 0.48 | ALDH1A1 (0.53) | NPSR1 | |
| SCHEMBL237236 | 0.48 | ALDH1A1 (0.44) | — | |
| Biphenyl SCHEMBL20271004 | 0.48 | ALDH1A1 (0.53) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743946-A1 | 5HT2B RECEPTOR ANTAGONISTS CONDENSED INDOLES | SMITHKLINE BEECHAM PLC (GB) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021844-A1 | 5HT2B RECEPTOR ANTAGONISTS CONDENSED INDOLES | SMITHKLINE BEECHAM PLC (GB) | 1995-08-17 | — | — | WO | disclosed |