Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003998 | 0.90 | MAPT (0.44) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL25847594 | 0.88 | MAPT (0.39) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL26310403 | 0.84 | MAPT (0.47) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL23999887 | 0.80 | MAPT (0.59) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24000021 | 0.78 | MAPT (0.45) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL23999935 | 0.74 | MAPT (0.42) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL25826536 | 0.73 | MAPT (0.43) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL26323174 | 0.70 | MAPT (0.36) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24000032 | 0.70 | MAPT (0.47) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL26310405 | 0.70 | MAPT (0.46) | MAPTPOLBSMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |