Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999887 | 0.84 | MAPT (0.59) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL25826535 | 0.84 | MAPT (0.44) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL24000021 | 0.83 | MAPT (0.45) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL26310403 | 0.79 | MAPT (0.47) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL24003998 | 0.79 | MAPT (0.44) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL25826534 | 0.77 | MAPT (0.38) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL23999934 | 0.73 | MAPT (0.40) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL25826537 | 0.72 | LMNA (0.46) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL25847594 | 0.72 | MAPT (0.39) | MAPTPOLBTSHRMAPK1KMT2A | |
| SCHEMBL25500798 | 0.71 | L3MBTL1 (0.39) | MAPTPOLBTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPT 3999/4885POLB 2609/4885TSHR 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.