Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 2/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.59 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.59 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.59 |
| ▸ | CDK8 | P49336 | 6/20 | 0.58 |
| ▸ | CCNC | P24863 | 5/20 | 0.58 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21750391 | 0.83 | GAK (0.55) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL21750416 | 0.81 | CDK8 (0.69) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL18658890 | 0.78 | PIK3CA (0.46) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL981901 | 0.78 | CDK8 (0.51) | GAKRIPK2COQ8ANLKCDK8 | |
| Hydrochloric Acid SCHEMBL983082 | 0.77 | CDK8 (0.50) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL24010219 | 0.77 | MAPKAPK2 (0.62) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL24003951 | 0.76 | ABCG2 (0.42) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL25053127 | 0.76 | HTR1A (0.70) | RIPK2CDK8MAPKAPK2HTR1AADRA1D | |
| SCHEMBL21750414 | 0.76 | CCNC (0.77) | GAKRIPK2COQ8ANLKCDK8 | |
| SCHEMBL24010750 | 0.75 | GAK (0.64) | GAKRIPK2COQ8ANLKCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |