Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106488 | 0.82 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL20193291 | 0.76 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL1162069 | 0.73 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL22764043 | 0.71 | CYP3A4 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL179349 | 0.71 | CDK2 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL2611034 | 0.71 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL2760432 | 0.71 | NOS3 (0.48) | NOS3NOS1NOS2 | |
| SCHEMBL22543158 | 0.71 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL20675998 | 0.71 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL30354636 | 0.71 | NOS3 (0.48) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346367-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346367-A1 | O-GLCNAC TRANSFERASE INHIBITORS AND USES THEREOF | OGT, OGA, UGGT1 | NOS3 1841/4885NOS1 1317/4885NOS2 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.