Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | DAO | P14920 | 1/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.78 |
| ▸ | CES1 | P23141 | 8/20 | 0.64 |
| ▸ | CES2 | O00748 | 7/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28601772 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL9705228 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28693411 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28646593 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL871104 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2762272 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28761872 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL29286711 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL578126 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL30648522 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2012149-B1 | RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO INC (JP) | 2018-02-14 | — | — | EP | disclosed |
| US-8961845-B2 | Optical compensation film, and polarizing plate and liquid crystal display employing the same | KONICA MINOLTA OPTO, INC. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130285280-A1 | OPTICAL COMPENSATION FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY EMPLOYING THE SAME | KONICA MINOLTA OPTO, INC. (JP) | 2013-10-31 | — | — | US | disclosed |
| US-8012384-B2 | Polarizing plate protective film and manufacturing method for the same | KONICA MINOLTA OPTO, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7854971-B2 | Cellulose ester film, production method of the same, polarizing plate and liquid crystal display | KONICA MINOLTA OPTO, INC. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20100297366-A1 | OPTICAL COMPENSATION FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY EMPLOYING THE SAME | KONICA MINOLTA OPTO, INC. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7803292-B2 | Optical film, optical film manufacturing method and optical film manufacturing device | KONICA MINOLTA OPTO, INC. (JP) | 2010-09-28 | — | — | US | disclosed |
| US-20100221457-A1 | OPTICAL COMPENSATION FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY EMPLOYING THE SAME | KONICA MINOLTA OPTO, INC. (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20090246416-A1 | OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090232977-A1 | Optical Film Treating Method, Optical Film Treating Apparatus, and Optical Film Producing Method | KONICA MONOLTA OPTO, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7466377-B2 | Retardation film, manufacturing method thereof, polarizing plate and liquid crystal display apparatus | KONICA MINOLTA OPTO, INC. (JP) | 2008-12-16 | — | — | US | disclosed |
| US-20080118667-A1 | Cellulose Ester Film, Production Method of the Same, Polarizing Plate and Liquid Crystal Display | KONICA MINOLTA OPTO, INC. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20080043176-A1 | Method of Manufacturing a Polarizing Plate Protective Film, Polarizing Plate Protective Film, Polarizing Plate, and Liquid Crystal Display Device | KONICA MINOLTA OPTO, INC. (JP) | 2008-02-21 | — | — | US | disclosed |
| US-20080013173-A1 | METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-20070145615-A1 | Optical film, optical film manufacturing method and optical film manufacturing device | KONICA MINOLTA OPTO, INC. (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070046865-A1 | Retardation film, manufacturing method thereof, polarizing plate and liquid crystal display apparatus | KONICA MINOLTA OPTO INC. | 2007-03-01 | — | — | US | disclosed |
| US-20060060997-A1 | Polarizing plate protective film and manufacturing method for the same | KONICA MINOLTA OPTO, INC. | 2006-03-23 | — | — | US | disclosed |
| EP-1353988-A4 | TRIMETHYLOLPROPANE ESTER-BASED PLASTICIZER COMPOSITION FOR POLYVINYL CHLORIDE RESIN | LG CHEMICAL LTD (KR) | 2005-01-19 | — | — | EP | disclosed |
| EP-1353988-A1 | TRIMETHYLOLPROPANE ESTER-BASED PLASTICIZER COMPOSITION FOR POLYVINYL CHLORIDE RESIN | LG Chem Ltd. (KR) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002053635-A1 | TRIMETHYLOLPROPANE ESTER-BASED PLASTICIZER COMPOSITION FOR POLYVINYL CHLORIDE RESIN | LG CHEM, LTD. (KR) | 2002-07-11 | — | — | WO | disclosed |