Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | DAO | P14920 | 1/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.78 |
| ▸ | CES1 | P23141 | 8/20 | 0.64 |
| ▸ | CES2 | O00748 | 7/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28601772 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2400344 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28693411 | 1.00 | TSHR (0.78) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28646593 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL871104 | 0.97 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2762272 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28761872 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL29286711 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL578126 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL30648522 | 0.92 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3597682-B1 | HETEROPHASIC PROPYLENE POLYMERIZATION MATERIAL AND PROPYLENE-BASED RESIN COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2023-09-27 | — | — | EP | disclosed |
| CN-112011129-B | Thermoplastic elastomer composition and method for producing same | 住友化学株式会社 | 2023-06-30 | — | — | CN | disclosed |
| US-11613601-B2 | Heterophasic propylene polymer material and propylene-based resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-03-28 | — | — | US | disclosed |
| US-11384232-B2 | Heterophasic propylene polymerization material | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-07-12 | — | — | US | disclosed |
| EP-3842489-B1 | HETEROPHASIC PROPYLENE POLYMER MATERIAL AND USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2022-04-13 | — | — | EP | disclosed |
| US-11186710-B2 | Thermoplastic elastomer composition and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-11-30 | — | — | US | disclosed |
| EP-3495420-B1 | HETEROPHASIC PROPYLENE POLYMERIZATION MATERIAL | SUMITOMO CHEMICAL CO (JP) | 2021-11-17 | — | — | EP | disclosed |
| EP-3842489-A1 | HETEROPHASIC PROPYLENE POLYMER MATERIAL AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-20210189110-A1 | HETEROPHASIC PROPYLENE POLYMER MATERIAL AND USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-24 | — | — | US | disclosed |
| US-20210047503-A1 | HETEROPHASIC PROPYLENE POLYMERIZATION MATERIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-02-18 | — | — | US | disclosed |
| CN-1982290-A | Fungicidal carboxamides | UNIV ARKANSAS (US) | 2007-06-20 | — | — | CN | disclosed |
| CN-1274724-C | Method of producing olefine polymer and its polymer | SINOPEC CORP (CN) | 2006-09-13 | — | — | CN | disclosed |
| CN-1800141-A | Ester admixture | LANXESS DEUTSCHLAND GMBH (DE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1241958-C | Propene polymers and preparation process thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2006-02-15 | — | — | CN | disclosed |
| CN-1218234-C | Free form code Chinese input method | LIANG CHUANREN (CN) | 2005-09-07 | — | — | CN | disclosed |
| CN-1213080-C | Catalyst for olefine polymerizing reaction and its components | CHINA PETROCHEMICAL CORP (CN) | 2005-08-03 | — | — | CN | disclosed |
| CN-1597714-A | Method of producing olefine polymer and its polymer | CHINA PETROCHEMICAL CORP (CN) | 2005-03-23 | — | — | CN | disclosed |
| CN-1566164-A | Propene polymers and preparation process thereof | SINOPEC CORP (CN) | 2005-01-19 | — | — | CN | disclosed |
| CN-1453298-A | Catalyst for olefine polymerizing reaction and its components | CHINA PETROCHEMICAL CORP (CN) | 2003-11-05 | — | — | CN | disclosed |
| EP-0489536-A2 | Olefin polymerisation catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-10 | — | — | EP | disclosed |