Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005860 | 0.82 | HTR2A (0.42) | HTR2AHTR2CHTR2BHTR1ADRD3 | |
| SCHEMBL25478605 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2BHTR1ADRD3 | |
| SCHEMBL25628791 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2BHTR1ADRD3 | |
| SCHEMBL25480350 | 0.79 | — | — | |
| SCHEMBL25478806 | 0.77 | — | — | |
| SCHEMBL25613537 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BHTR1ADRD3 | |
| SCHEMBL24774501 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BHTR1ADRD3 | |
| SCHEMBL25478877 | 0.76 | DRD4 (0.43) | DRD4MEN1CYP3A4KMT2ACYP1A2 | |
| SCHEMBL24005490 | 0.76 | TAAR1 (0.40) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL20655942 | 0.75 | CHRNB2 (0.43) | HTR2AHTR2CHTR2BHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |