Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 11/20 | 0.40 |
| ▸ | HTR2B | P41595 | 11/20 | 0.40 |
| ▸ | HTR2A | P28223 | 9/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613539 | 0.78 | TAAR1 (0.40) | TAAR1HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL24005483 | 0.76 | HTR2A (0.39) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL3313346 | 0.76 | TAAR1 (0.42) | TAAR1HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL25480350 | 0.73 | — | — | |
| SCHEMBL30531522 | 0.71 | TAAR1 (0.35) | TAAR1HTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL24005493 | 0.70 | — | — | |
| SCHEMBL30692842 | 0.70 | SIGMAR1 (0.41) | KCNH2 | |
| SCHEMBL28537471 | 0.68 | HTR2C (0.47) | HTR2CSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL25354904 | 0.67 | SLC6A2 (0.38) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL23943757 | 0.67 | SLC6A2 (0.38) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |