Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624526 | 0.83 | CYP2C19 (0.40) | LTA4HHRH3HTR6KCNH2 | |
| SCHEMBL25624610 | 0.73 | CYP3A4 (0.42) | NTRK1 | |
| SCHEMBL24005758 | 0.73 | MEN1 (0.45) | NTRK1 | |
| SCHEMBL25627483 | 0.71 | CYP1A2 (0.33) | HTR6 | |
| SCHEMBL25613052 | 0.70 | ALDH1A1 (0.44) | HRH3 | |
| SCHEMBL24005765 | 0.64 | LTA4H (0.48) | LTA4HHRH3 | |
| SCHEMBL16621346 | 0.63 | LTA4H (0.46) | LTA4HHRH3 | |
| SCHEMBL25613054 | 0.62 | LTA4H (0.45) | LTA4HHRH3 | |
| SCHEMBL2319084 | 0.62 | LTA4H (0.60) | LTA4HHRH3 | |
| SCHEMBL25624434 | 0.62 | MERTK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |