Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625964 | 0.80 | ULK1 (0.48) | ULK1ADORA1IRAK4HPGDSADORA3 | |
| SCHEMBL24005917 | 0.75 | GSK3A (0.48) | ALDH1A1 | |
| SCHEMBL19654314 | 0.74 | ULK1 (0.71) | ULK1IRAK4SYK | |
| SCHEMBL11286572 | 0.71 | AXL (0.39) | ADORA1IRAK4ADORA2ABRD4CLK4 | |
| SCHEMBL24005750 | 0.71 | PIK3C3 (0.46) | IRAK4ADORA3ALDH1A1CLK4PAK4 | |
| SCHEMBL24005740 | 0.70 | JAK3 (0.41) | IRAK4BRD4JAK2MAPK1 | |
| SCHEMBL19654322 | 0.70 | ULK1 (0.72) | ULK1SYK | |
| SCHEMBL19654316 | 0.69 | ULK1 (0.71) | ULK1IRAK4BRD4MAPK1SYK | |
| SCHEMBL9887640 | 0.68 | AXL (0.42) | ADORA1IRAK4ADORA2ABRD4CLK4 | |
| SCHEMBL24005741 | 0.68 | RIPK1 (0.42) | ADORA1IRAK4ADORA2ABRD4CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |