Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.59 |
| ▸ | DNMT3A | Q9Y6K1 | 7/20 | 0.59 |
| ▸ | DNMT3L | Q9UJW3 | 5/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999636 | 0.93 | MAPT (0.53) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL30180473 | 0.93 | MAPT (0.53) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL24006299 | 0.93 | DNMT1 (0.56) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL23999596 | 0.87 | MAPT (0.48) | DNMT1DNMT3AMAPKAPK2MAPTKMT2A | |
| SCHEMBL30180296 | 0.87 | MAPT (0.48) | DNMT1DNMT3AMAPKAPK2MAPTKMT2A | |
| SCHEMBL24009943 | 0.87 | DNMT1 (0.49) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL30180365 | 0.87 | MAPT (0.45) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL23999440 | 0.87 | MAPT (0.45) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL23999637 | 0.85 | MAPT (0.45) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 | |
| SCHEMBL30180369 | 0.85 | MAPT (0.45) | DNMT1DNMT3ADNMT3LEHMT1MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226477-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |