Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006144 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL5139240 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL22539528 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL19088619 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL25670286 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL23817240 | 0.77 | ALDH1A1 (0.61) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL27906426 | 0.74 | ALDH1A1 (0.57) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL1554123 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL29294170 | 0.72 | ALDH1A1 (0.59) | ALDH1A1HCAR2CA12CA1CA2 | |
| SCHEMBL3094482 | 0.72 | HCAR2 (0.57) | ALDH1A1HCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226465-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-11-11 | — | — | WO | disclosed |