Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14675315 | 0.89 | HCAR2 (0.53) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL9001891 | 0.86 | HCAR2 (0.61) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL6708209 | 0.83 | HCAR2 (0.57) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL4065633 | 0.80 | HCAR2 (0.62) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL6966475 | 0.80 | HCAR2 (0.54) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL7079046 | 0.80 | HCAR2 (0.54) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL9744614 | 0.79 | HCAR2 (0.47) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL6971651 | 0.79 | HCAR2 (0.53) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL6133091 | 0.79 | HCAR2 (0.61) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL9650418 | 0.79 | HCAR2 (0.61) | HCAR2LMNAALDH1A1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183781-A2 | LEGIONAMINIC ACID GLYCOSYLTRANSFERASES FOR CHEMOENZYMATIC SYNTHESIS OF GLYCANS AND GLYCOCONJUGATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-28 | — | — | WO | disclosed |
| US-9310366-B2 | Anthrax carbohydrates, synthesis and uses thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20130260402-A1 | ANTHRAX CARBOHYDRATES, SYNTHESIS AND USES THEREOF | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (WASHINGTON D.C.) | 2013-10-03 | — | — | US | disclosed |
| US-8420607-B2 | Anthrax carbohydrates, synthesis and uses thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100233174-A9 | Anthrax carbohydrates, synthesis and uses thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (WASHINGTON D.C.) | 2010-09-16 | — | — | US | disclosed |
| US-20090246200-A1 | Anthrax carbohydrates, synthesis and uses thereof | CARLSON RUSSELL W | 2009-10-01 | — | — | US | disclosed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233174-A9 | Anthrax carbohydrates, synthesis and uses thereof | ANTXR2, MGAM, CA14 | HCAR2 683/4885LMNA 2601/4885ALDH1A1 2690/4885 |
| US-20090246200-A1 | Anthrax carbohydrates, synthesis and uses thereof | ANTXR2, MGAM, CA14 | HCAR2 683/4885LMNA 2601/4885ALDH1A1 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.