SCHEMBL24006348

SCHEMBL24006348

CCOCCOC(=O)CCONC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
THRB P10828 1/20 0.43
DGKA P23743 1/20 0.41
EPHX2 P34913 2/20 0.40
HSD17B10 Q99714 1/20 0.40
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6203890 0.84 GAA (0.52) ALDH1A1TSHRDGKAHSD17B10MGAM
SCHEMBL3899494 0.82 DGKA (0.45) ALDH1A1DGKAEPHX2MGAMGAA
SCHEMBL1301905 0.82 ALDH1A1 (0.62) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL4818015 0.82 ALDH1A1 (0.56) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL2303872 0.80 ALDH1A1 (0.60) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL3879046 0.80 ALDH1A1 (0.60) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL1302166 0.78 DGKA (0.65) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL181474 0.78 ALDH1A1 (0.58) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL29151568 0.78 DGKA (0.59) ALDH1A1TSHRTHRBDGKAEPHX2
SCHEMBL9598368 0.78 ALDH1A1 (0.62) ALDH1A1TSHRTHRBDGKAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692102-B1 HIGH WET FAST DISPERSE DYE MIXTURES DYSTAR COLOURS DISTRIB GMBH (DE) 2021-11-10 EP disclosed