Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.71 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176129 | 0.98 | ADRB1 (0.73) | ADRB1FFAR4HRH4MAPTKDM4E | |
| SCHEMBL30582925 | 0.89 | ADRB1 (0.62) | ADRB1FFAR4HRH4MAPTKDM4E | |
| SCHEMBL30582877 | 0.89 | ADRB1 (0.62) | ADRB1FFAR4HRH4MAPTKDM4E | |
| Tert-Butyl Formate SCHEMBL27852289 | 0.85 | ADRB1 (0.54) | ADRB1FFAR4HRH4MAPTKDM4E | |
| SCHEMBL1998032 | 0.85 | ADRB1 (0.69) | ADRB1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL1901605 | 0.85 | ADRB1 (0.69) | ADRB1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL210342 | 0.83 | ADRB1 (1.00) | ADRB1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL30567166 | 0.83 | ADRB1 (1.00) | ADRB1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL24363082 | 0.83 | ADRB1 (0.68) | ADRB1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL12968838 | 0.83 | ADRB1 (0.68) | ADRB1FFAR4HRH4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| WO-2021224864-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | ADRB1 4000/4885FFAR4 1055/4885HRH4 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.