Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 1.00 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | NCF1 | P14598 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210342 | 1.00 | ADRB1 (1.00) | ADRB1KARS1ADRB2NCF1HTR3E | |
| Hydrochloric Acid SCHEMBL3327814 | 0.98 | ADRB1 (0.97) | ADRB1KARS1ADRB2NCF1HTR3E | |
| Hydrochloric Acid SCHEMBL31061195 | 0.98 | ADRB1 (0.97) | ADRB1KARS1ADRB2NCF1HTR3E | |
| SCHEMBL31061377 | 0.91 | ADRB1 (0.83) | ADRB1KARS1ADRB2NCF1HTR3E | |
| SCHEMBL18176129 | 0.85 | ADRB1 (0.73) | ADRB1KARS1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL30328111 | 0.84 | ADRB1 (0.72) | ADRB1KARS1ADRB2NCF1ALDH1A1 | |
| SCHEMBL11916030 | 0.84 | ADRB1 (0.72) | ADRB1KARS1ADRB2NCF1HTR1D | |
| SCHEMBL24008459 | 0.83 | ADRB1 (0.71) | ADRB1KARS1ALDH1A1MAPTKDM4E | |
| SCHEMBL1901605 | 0.82 | ADRB1 (0.69) | ADRB1KARS1ALDH1A1MAPTKDM4E | |
| SCHEMBL1998032 | 0.82 | ADRB1 (0.69) | ADRB1KARS1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101008-A1 | HETEROBIFUNCTIONAL MOLECULES FOR BINDING CCR2 AND METHODS OF TREATING MEDICAL CONDITIONS USING SAME | Solu Therapeutics, Inc. | 2025-03-27 | — | — | US | disclosed |
| WO-2024165050-A1 | PROTEOLYSIS-TARGETING CHIMERA (PROTAC) COMPOUNDS AND USES THEREOF FIELD | AUBRAK THERAPEUTICS (CN) | 2024-08-15 | — | — | WO | disclosed |
| CN-111787916-B | Dihydroceramide desaturase inhibitors for treating diseases | 森陶鲁斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101008-A1 | HETEROBIFUNCTIONAL MOLECULES FOR BINDING CCR2 AND METHODS OF TREATING MEDICAL CONDITIONS USING SAME | CCR2, CCR5, CCL2 | ADRB1 152/4885KARS1 2236/4885ADRB2 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.