Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 3/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564635 | 0.86 | KDM4E (0.65) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24373525 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29479071 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7122711 | 0.75 | NQO2 (0.59) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7774725 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30013215 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27842045 | 0.75 | TNKS (0.48) | KDM4EALDH1A1TNKSTNKS2PARP2 | |
| SCHEMBL1353177 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24008926 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7748193 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780849-B2 | Imino sulfanone inhibitors of ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-11780849-B2 | Imino sulfanone inhibitors of ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| CN-115996912-A | Iminothiolanone inhibitors of ENPP1 | 沃拉斯查疗法公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4146344-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | Volastra Therapeutics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| US-20230002406-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| WO-2021225969-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780849-B2 | Imino sulfanone inhibitors of ENPP1 | ENPP1, ENPP3, SMPD1 | KDM4E 3407/4885ALDH1A1 1567/4885MEN1 1249/4885 |
| US-20230002406-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | ENPP1, ENPP3, SMPD1 | KDM4E 3407/4885ALDH1A1 1567/4885MEN1 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.