Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.61 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.61 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.61 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.61 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.61 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.61 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.61 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.61 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.61 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.61 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400914 | 1.00 | TTR (0.71) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL2354263 | 0.90 | TTR (0.62) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL15483207 | 0.90 | TTR (0.73) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL12030514 | 0.90 | TTR (0.62) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL2354266 | 0.90 | TTR (0.62) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL8349648 | 0.85 | TTR (0.55) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL19452381 | 0.85 | TTR (0.55) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL9927101 | 0.84 | TTR (1.00) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL9927100 | 0.84 | TTR (1.00) | TTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL4454526 | 0.82 | TUBB4A (0.77) | TTRKDM4ETUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230678-A1 | ORGANIC FRAMEWORK | INSILICOTECH CO., LTD (KR) | 2011-09-22 | — | — | US | claimed |
| WO-2010056092-A9 | ORGANIC FRAMEWORK | (주)인실리코텍 (KR) | 2010-07-29 | — | — | WO | claimed |
| WO-2010056092-A2 | ORGANIC FRAMEWORK | (주)인실리코텍 (KR) | 2010-05-20 | — | — | WO | claimed |
| US-20110230678-A1 | ORGANIC FRAMEWORK | INSILICOTECH CO., LTD (KR) | 2011-09-22 | — | — | US | disclosed |
| WO-2010056092-A9 | ORGANIC FRAMEWORK | (주)인실리코텍 (KR) | 2010-07-29 | — | — | WO | disclosed |
| WO-2010056092-A2 | ORGANIC FRAMEWORK | (주)인실리코텍 (KR) | 2010-05-20 | — | — | WO | disclosed |
| US-6361884-B1 | POLYMERS FOR SEMICONDUCTORS | COVIAN ORGANIC SEMICONDUCTOR GMBH (DE) | 2002-03-26 | — | — | US | disclosed |
| EP-0882082-B1 | PARTLY CONJUGATED POLYMERS WITH SPIRO CENTRES AND THEIR USE AS ELECTRO-LUMINESCENT MATERIALS | AXIVA GMBH (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-0882082-A1 | PARTY CONJUGATED POLYMERS WITH SPIRO CENTRES AND THEIR USE AS ELECTRO-LUMINESCENT MATERIALS | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997031048-A1 | PARTY CONJUGATED POLYMERS WITH SPIRO CENTRES AND THEIR USE AS ELECTRO-LUMINESCENT MATERIALS | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) | 1997-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230678-A1 | ORGANIC FRAMEWORK | MCM4, DBF4, ORC3 | TTR 945/4885KDM4E 2714/4885TUBB4A 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.