⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163351 | 0.72 | — | — | |
| SCHEMBL5705399 | 0.70 | — | — | |
| SCHEMBL517101 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL4482101 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL392381 | 0.69 | — | — | |
| SCHEMBL24403554 | 0.69 | — | — | |
| SCHEMBL28980851 | 0.67 | — | — | |
| SCHEMBL12856768 | 0.65 | — | — | |
| Dimethylamine SCHEMBL5200560 | 0.65 | — | — | |
| SCHEMBL27964409 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226629-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |