Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633918 | 0.89 | EPHX1 (0.44) | EPHX1DRD4MCHR1EPHX2TP53 | |
| SCHEMBL24011500 | 0.87 | EPHX1 (0.53) | EPHX1DRD4MCHR1EPHX2TP53 | |
| SCHEMBL24011708 | 0.87 | EPHX1 (0.53) | EPHX1DRD4MCHR1EPHX2TP53 | |
| SCHEMBL24011707 | 0.87 | EPHX1 (0.53) | EPHX1DRD4MCHR1EPHX2TP53 | |
| SCHEMBL24011382 | 0.85 | EPHX1 (0.64) | EPHX1DRD4EPHX2TP53RAB9A | |
| SCHEMBL26764199 | 0.79 | EPHX1 (0.46) | EPHX1DRD4MCHR1TP53RAB9A | |
| SCHEMBL26764306 | 0.79 | EPHX1 (0.46) | EPHX1DRD4MCHR1TP53RAB9A | |
| SCHEMBL24011394 | 0.77 | MCHR1 (0.52) | EPHX1DRD4MCHR1EPHX2RAB9A | |
| SCHEMBL26102875 | 0.77 | RAB9A (0.53) | MCHR1EPHX2TP53RAB9ANPC1 | |
| SCHEMBL24011160 | 0.76 | EPHX1 (0.69) | EPHX1DRD4MCHR1EPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | EPHX1 3913/4885DRD4 3923/4885MCHR1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.