SCHEMBL24011859

SCHEMBL24011859

Cc1ccc(Oc2cccc(Oc3ccc(C)cc3)c2N2C(=O)c3cc(Oc4ccccc4)c4c5c(Oc6ccccc6)cc6c7c(cc(Oc8ccccc8)c(c8c(Oc9ccccc9)cc(c3c48)C2=O)c75)C(=O)N(c2c(Oc3ccc(C)cc3)cccc2Oc2ccc(C)cc2)C6=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.47
▸ KMT2A Q03164 5/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ ALDH1A1 P00352 4/20 0.41
▸ MAPT P10636 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ HTT P42858 3/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ FNTA P49354 1/20 0.37
▸ FNTB P49356 1/20 0.37
▸ BRD4 O60885 2/20 0.37
▸ POLB P06746 1/20 0.37
▸ LPAR1 Q92633 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24012119 0.88 MEN1 (0.41) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL24011861 0.86 GAA (0.40) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL10021803 0.86 KMT2A (0.56) MEN1KMT2AALDH1A1GAAHTT
SCHEMBL13498707 0.86 DPP4 (0.46) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL24012201 0.85 MAPK14 (0.36) MEN1KMT2A
SCHEMBL23772375 0.83 CA12 (0.35) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL24011913 0.82 RXFP1 (0.35) CYP1A2CYP2C9CYP2C19
SCHEMBL25014573 0.81 NR1H2 (0.35) MEN1KMT2AALDH1A1MAPTBRD4
SCHEMBL24011822 0.81 GSTP1 (0.40) KMT2AALDH1A1BRD4
SCHEMBL902459 0.80 ANPEP (0.49) LMNAMAPTBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES Konica Minolta, Inc. (JP) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES IGF1R, IK, BMI1 MEN1 44/4885KMT2A 1999/4885SMN1; SMN2 2162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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