SCHEMBL24012201

SCHEMBL24012201

O=C1c2cc(Oc3ccccc3)c3c4c(Oc5ccccc5)cc5c6c(cc(Oc7ccccc7)c(c7c(Oc8ccccc8)cc(c2c37)C(=O)N1c1c(Oc2ccc(C(F)(F)F)cc2)cccc1Oc1ccc(C(F)(F)F)cc1)c64)C(=O)N(c1c(Oc2ccc(C(F)(F)F)cc2)cccc1Oc1ccc(C(F)(F)F)cc1)C5=O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 2/20 0.36
▸ RXFP1 Q9HBX9 1/20 0.36
▸ BACE1 P56817 1/20 0.36
▸ NR3C1 P04150 1/20 0.36
▸ PGR P06401 1/20 0.36
▸ AR P10275 1/20 0.36
▸ ESR2 Q92731 1/20 0.36
▸ PPARG P37231 1/20 0.35
▸ PPARA Q07869 1/20 0.35
▸ SCN8A Q9UQD0 2/20 0.35
▸ SCN10A Q9Y5Y9 2/20 0.35
▸ NR1H2 P55055 1/20 0.34
▸ NR1H3 Q13133 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ LTA4H P09960 1/20 0.34
▸ EPHX2 P34913 1/20 0.34
▸ CHRM5 P08912 2/20 0.34
▸ CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24011913 0.92 RXFP1 (0.35) RXFP1NR3C1PGRARESR2
SCHEMBL24011855 0.91 ALDH1A1 (0.36) PPARGPPARACHRM5CHRM3
SCHEMBL24012120 0.85 PPARG (0.36) PPARGPPARA
SCHEMBL24011859 0.85 MEN1 (0.47) MEN1KMT2A
SCHEMBL24011861 0.84 GAA (0.40) NR1H2MEN1KMT2A
SCHEMBL23772375 0.83 CA12 (0.35) NR1H2MEN1KMT2A
SCHEMBL24012119 0.81 MEN1 (0.41) NR1H2NR1H3MEN1KMT2A
SCHEMBL24012118 0.81 HPGD (0.37) NR1H2NR1H3MEN1KMT2A
SCHEMBL24011822 0.79 GSTP1 (0.40) NR1H2KMT2A
SCHEMBL25014573 0.79 NR1H2 (0.35) NR1H2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES Konica Minolta, Inc. (JP) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES IGF1R, IK, BMI1 MAPK14 3029/4885RXFP1 1526/4885BACE1 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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