SCHEMBL24011913

SCHEMBL24011913

O=C1c2cc(Oc3ccccc3)c3c4c(Oc5ccccc5)cc5c6c(cc(Oc7ccccc7)c(c7c(Oc8ccccc8)cc(c2c37)C(=O)N1c1c(Oc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cccc1Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c64)C(=O)N(c1c(Oc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cccc1Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C5=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 1/20 0.35
▸ TLR8 Q9NR97 4/20 0.34
▸ NR1H2 P55055 1/20 0.34
▸ SCN8A Q9UQD0 3/20 0.33
▸ SCN10A Q9Y5Y9 3/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ PPARG P37231 2/20 0.33
▸ PPARA Q07869 2/20 0.33
▸ NR3C1 P04150 1/20 0.33
▸ PGR P06401 1/20 0.33
▸ AR P10275 1/20 0.33
▸ ESR2 Q92731 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ RHOA P61586 1/20 0.32
▸ TLR7 Q9NYK1 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24012201 0.92 MAPK14 (0.36) RXFP1NR1H2SCN8ASCN10APPARG
SCHEMBL24012120 0.89 PPARG (0.36) L3MBTL1PPARGPPARATLR7
SCHEMBL24011855 0.83 ALDH1A1 (0.36) L3MBTL1PPARGPPARA
SCHEMBL23772375 0.82 CA12 (0.35) NR1H2NPSR1
SCHEMBL24011859 0.82 MEN1 (0.47) CYP1A2CYP2C9CYP2C19
SCHEMBL24011861 0.81 GAA (0.40) NR1H2CYP1A2CYP2C9CYP2C19
SCHEMBL25014573 0.78 NR1H2 (0.35) NR1H2
SCHEMBL13498707 0.78 DPP4 (0.46) L3MBTL1NPSR1
SCHEMBL24011822 0.78 GSTP1 (0.40) NR1H2
SCHEMBL24011933 0.77 BRD4 (0.37) RXFP1L3MBTL1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES Konica Minolta, Inc. (JP) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES IGF1R, IK, BMI1 RXFP1 1526/4885TLR8 4404/4885NR1H2 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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