Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287232 | 0.88 | HTR2C (0.52) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL12849550 | 0.86 | PDK1 (0.52) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL23364640 | 0.86 | PDK1 (0.52) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL5517082 | 0.86 | HTR2C (0.64) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL5517077 | 0.86 | HTR2C (0.64) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL10053573 | 0.86 | HTR2C (0.64) | HTR2CPDK1PDK2PDK3PDK4 | |
| SCHEMBL1150967 | 0.86 | POLB (0.48) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3644432 | 0.86 | POLB (0.48) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7370454 | 0.86 | POLB (0.48) | HTR2CPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1269759 | 0.86 | POLB (0.48) | HTR2CPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355890-B1 | HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2021-11-10 | — | — | EP | disclosed |