SCHEMBL24012143

SCHEMBL24012143

O=C1c2cc(Oc3ccc(S(=O)(=O)O)cc3)c3c4c(Oc5ccc(S(=O)(=O)O)cc5)cc5c6c(cc(Oc7ccc(S(=O)(=O)O)cc7)c(c7c(Oc8ccc(S(=O)(=O)O)cc8)cc(c2c37)C(=O)N1c1c(Oc2c(F)c(F)c(F)c(F)c2F)cccc1Oc1c(F)c(F)c(F)c(F)c1F)c64)C(=O)N(c1c(Oc2c(F)c(F)c(F)c(F)c2F)cccc1Oc1c(F)c(F)c(F)c(F)c1F)C5=O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.31
▸ HPGD P15428 2/20 0.31
▸ ALDH1A1 P00352 3/20 0.31
▸ MEN1 O00255 2/20 0.30
▸ MAPT P10636 2/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23772375 0.87 CA12 (0.35) KMT2AHPGDALDH1A1MEN1MAPT
SCHEMBL24012248 0.83 ANPEP (0.31) —
SCHEMBL17448853 0.80 ANPEP (0.46) KMT2AALDH1A1MEN1MAPTLMNA
SCHEMBL24012157 0.78 KMT2A (0.36) KMT2AHPGDALDH1A1MEN1MAPT
SCHEMBL24011834 0.78 LMNA (0.31) KMT2AALDH1A1MEN1MAPTLMNA
SCHEMBL25868505 0.78 ANPEP (0.43) ALDH1A1MAPTLMNA
SCHEMBL24012156 0.78 MMP9 (0.33) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL24012192 0.77 NTRK1 (0.34) KMT2AALDH1A1MEN1MAPTLMNA
SCHEMBL24011892 0.77 — —
SCHEMBL24011958 0.77 NR1H3 (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES Konica Minolta, Inc. (JP) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210351356-A1 IMIDE DERIVATIVE, LUMINESCENT COMPOSITION CONTAINING SAME, LUMINOUS THIN FILM, AND LUMINOUS PARTICLES IGF1R, IK, BMI1 KMT2A 1999/4885HPGD 3687/4885ALDH1A1 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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