SCHEMBL24012402

SCHEMBL24012402

CCC(=O)[C@H](CCCCN=[N+]=[N-])NC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.32
▸ FOLH1 Q04609 3/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ CHRM4 P08173 1/20 0.31
▸ CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22375469 0.86 FOLH1 (0.33) FOLH1CHRM2CHRM4CHRM1
SCHEMBL21465910 0.85 ALB (0.39) FOLH1
SCHEMBL22375760 0.84 ADRB2 (0.31) CNR2FOLH1
SCHEMBL13539964 0.84 CHRM2 (0.47) FOLH1CHRM2CHRM4CHRM1
SCHEMBL14950991 0.83 FOLH1 (0.32) CNR2FOLH1CHRM2CHRM4CHRM1
SCHEMBL13448062 0.83 FOLH1 (0.39) CNR2FOLH1
SCHEMBL16446180 0.83 FOLH1 (0.39) CNR2FOLH1
SCHEMBL15706851 0.83 FOLH1 (0.32) CNR2FOLH1CHRM2CHRM4CHRM1
SCHEMBL24012449 0.83 FOLH1 (0.30) FOLH1
SCHEMBL24012407 0.81 CNR2 (0.32) CNR2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210346509-A1 GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof ASTRAZENECA AB (SE) 2021-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210346509-A1 GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof GLP1R, GIPR, GRPR CNR2 1908/4885FOLH1 149/4885CHRM2 4049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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