Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012402 | 0.84 | CNR2 (0.32) | CHRM2CHRM4CHRM1FOLH1 | |
| SCHEMBL22375469 | 0.83 | FOLH1 (0.33) | CHRM2CHRM4CHRM1FOLH1 | |
| SCHEMBL22375760 | 0.82 | ADRB2 (0.31) | FOLH1CTSLCTSB | |
| SCHEMBL24012449 | 0.81 | FOLH1 (0.30) | FOLH1 | |
| SCHEMBL21566740 | 0.76 | SIRT6 (0.57) | CHRM2CHRM4CHRM1SIRT6SIRT1 | |
| SCHEMBL13998248 | 0.76 | SIRT6 (0.57) | CHRM2CHRM4CHRM1SIRT6SIRT1 | |
| SCHEMBL14771639 | 0.74 | SIRT6 (0.52) | CHRM2CHRM4CHRM1SIRT6SIRT1 | |
| SCHEMBL13539965 | 0.74 | NOS1 (0.40) | CHRM2CHRM4CHRM1BLM | |
| SCHEMBL14950991 | 0.74 | FOLH1 (0.32) | CHRM2CHRM4CHRM1FOLH1 | |
| SCHEMBL15706851 | 0.74 | FOLH1 (0.32) | CHRM2CHRM4CHRM1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9188584-B2 | Capture agents and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-11-17 | — | — | US | disclosed |
| US-8906830-B2 | Capture agents and related compositions, methods and systems | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-12-09 | — | — | US | disclosed |
| US-20110263515-A1 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-27 | — | — | US | disclosed |
| US-20100009896-A1 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009896-A1 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | HAVCR2, CD47, EPCAM | CHRM2 2130/4885CHRM4 1101/4885CHRM1 2599/4885 |
| US-20110263515-A1 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | HAVCR2, CD47, EPCAM | CHRM2 2130/4885CHRM4 1101/4885CHRM1 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.