Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24013113 | 0.88 | CYP4F2 (0.52) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL24012965 | 0.85 | MAOB (0.41) | CYP4F2CYP4A11DRD1MAOBACHE | |
| SCHEMBL24012856 | 0.83 | PDE4B (0.42) | NPC1RAB9AMAOBCYP2D6ACHE | |
| SCHEMBL24012651 | 0.82 | LSS (0.38) | CYP4F2CYP4A11MEN1KMT2ADRD1 | |
| SCHEMBL24012527 | 0.81 | CYP4F2 (0.42) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL177024 | 0.81 | CYP4F2 (0.43) | CYP4F2CYP4A11NPC1RAB9AHTR3A | |
| SCHEMBL28989533 | 0.81 | MAOB (0.46) | CYP4F2CYP4A11MEN1NPC1RAB9A | |
| SCHEMBL24012458 | 0.80 | MAPT (0.47) | MEN1RAB9AKMT2ADRD1L3MBTL1 | |
| SCHEMBL176753 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11HTR3ACNR1CNR2 | |
| SCHEMBL177022 | 0.80 | HTR3A (0.48) | CYP4F2CYP4A11KMT2AHTR3ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224320-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2021-11-11 | — | — | WO | disclosed |