SCHEMBL240153

SCHEMBL240153

C=CC(=O)OC1c2ccccc2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
THRB P10828 1/20 0.38
AKT1 P31749 1/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
GAA P10253 1/20 0.33
TYMS P04818 1/20 0.33
MAPT P10636 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31390251 1.00 POLB (0.46) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL9610452 0.88 POLB (0.37) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL12735511 0.82 RET (0.39) POLBTHRBAKT1TSHRLMNA
SCHEMBL22195126 0.82 THRB (0.36) POLBTHRBKMT2ACYP1A2MAPT
SCHEMBL25255644 0.82 POLB (0.36) POLBKMT2AMEN1
SCHEMBL27777776 0.78 POLB (0.53) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL7646709 0.77 POLB (0.42) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL10102819 0.77 MAPT (0.34) POLBHDAC3HDAC8HDAC6THRB
SCHEMBL12433516 0.77 THRB (0.53) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL20917779 0.76 POLB (0.52) POLBHDAC3HDAC4HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190105938-A1 SECURITY ELEMENTS AND METHOD OF MANUFACTURE THEREOF DE LA RUE INTERNATIONAL LIMITED (GB) 2019-04-11 US disclosed
CN-105542795-B Chiral polymerizable liquid crystal composition and its application 江苏和成新材料有限公司 2018-09-04 CN disclosed
US-10007178-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-10007178-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-26 US disclosed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-9869931-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-9846360-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-19 US disclosed
US-9846360-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-12-19 US disclosed
US-9760010-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
US-9760010-B2 Patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-12 US disclosed
CN-101620870-A Optical information recording medium SONY CORP 2010-01-06 CN disclosed
CN-101620871-A Optical information recording medium SONY CORP 2010-01-06 CN disclosed
US-20090292070-A1 Material composition and optical elements using the same OLYMPUS CORPORATION (JP) 2009-11-26 US disclosed
WO-2009134594-A1 OPTICAL FILMS COMPRISING FLUORENOL (METH)ACRYLATE MONOMER 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-05 WO disclosed
US-20090270576-A1 OPTICAL FILMS COMPRISING FLUORENOL (METH)ACRYLATE MONOMER 3M INNOVATIVE PROPERTIES COMPANY 2009-10-29 US disclosed
US-20090270576-A1 OPTICAL FILMS COMPRISING FLUORENOL (METH)ACRYLATE MONOMER 3M INNOVATIVE PROPERTIES COMPANY 2009-10-29 US disclosed
US-20090264589-A1 Material composition and optical elements using the same OLYMPUS CORPORATION (JP) 2009-10-22 US disclosed
CN-100503733-C Transparent composite composition SUMITOMO BAKELITE CO (JP) 2009-06-24 CN disclosed
CN-1606600-A Transparent composite composition SUMITOMO BAKELITE CO (JP) 2005-04-13 CN disclosed
US-4122113-A 9-Fluorenyl acrylates XEROX CORPORATION (US) 1978-10-24 US disclosed