⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18594704 | 0.79 | — | — | |
| SCHEMBL24016005 | 0.76 | — | — | |
| SCHEMBL526284 | 0.74 | CTSS (0.32) | — | |
| SCHEMBL25963653 | 0.74 | — | — | |
| SCHEMBL24476189 | 0.73 | — | — | |
| SCHEMBL21448000 | 0.73 | — | — | |
| SCHEMBL7132286 | 0.73 | TDP1 (0.31) | — | |
| SCHEMBL16558980 | 0.72 | — | — | |
| SCHEMBL20960299 | 0.72 | — | — | |
| SCHEMBL17245269 | 0.71 | CA2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053449-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | NOVARTIS AG (CH) | 2023-02-23 | — | — | US | disclosed |
| US-11453870-B2 | Ligase fusion proteins and application thereof | GENEQUANTUM HEALTHCARE (SUZHOU) CO. LTD. (CN) | 2022-09-27 | — | — | US | disclosed |
| US-20210346387-A1 | ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST | NOVARTIS AG (CH) | 2021-11-11 | — | — | US | disclosed |