Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526613 | 1.00 | PTGDR2 (0.50) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL6930798 | 0.90 | PTGDR2 (0.54) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL6924104 | 0.90 | PTGDR2 (0.54) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL11603441 | 0.86 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL11600497 | 0.86 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL11600503 | 0.86 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL15578425 | 0.84 | PTGDR2 (0.52) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL13165574 | 0.82 | MTNR1A (0.47) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL8457592 | 0.82 | PTGDR2 (0.48) | PTGDR2MTNR1AMTNR1BSMN1; SMN2NPSR1 | |
| SCHEMBL25587333 | 0.81 | CCR2 (0.39) | PTGDR2NPSR1PARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |