Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
| ▸ | APOL1 | O14791 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584595 | 0.81 | SLC10A1 (0.32) | SLC10A1APOL1 | |
| SCHEMBL13941597 | 0.78 | — | — | |
| SCHEMBL976812 | 0.74 | MME (0.44) | ALDH1A1 | |
| SCHEMBL23715196 | 0.74 | MME (0.41) | ALDH1A1 | |
| SCHEMBL18214755 | 0.72 | EPHX1 (0.39) | ALDH1A1 | |
| SCHEMBL20738725 | 0.71 | — | — | |
| SCHEMBL22644386 | 0.71 | — | — | |
| SCHEMBL22633641 | 0.71 | — | — | |
| SCHEMBL21843744 | 0.70 | — | — | |
| SCHEMBL15461395 | 0.69 | DPP4 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |