Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 9/20 | 0.48 |
| ▸ | TNF | P01375 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572408 | 0.80 | SIGMAR1 (0.45) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL31622374 | 0.76 | GFER (0.46) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL15426200 | 0.76 | DHODH (0.61) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL14637660 | 0.75 | SIGMAR1 (0.43) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL14637434 | 0.74 | PLK1 (0.39) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL15905254 | 0.73 | SIGMAR1 (0.44) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL18487239 | 0.70 | SIGMAR1 (0.44) | NOD1TNFNPC1RAB9AGFER | |
| SCHEMBL5053533 | 0.69 | MAPK1 (0.49) | DHODH | |
| SCHEMBL3312480 | 0.69 | MAPK1 (0.49) | DHODH | |
| SCHEMBL5051427 | 0.69 | ALDH1A1 (0.53) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |