Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15745622 | 0.85 | NPSR1 (0.77) | NPSR1CA12CA4CA7CA9 | |
| SCHEMBL25591544 | 0.84 | ALDH1A1 (0.47) | NPSR1HTTKDM4E | |
| SCHEMBL14562253 | 0.81 | NPSR1 (0.56) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL9297778 | 0.80 | NPSR1 (0.54) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL12344353 | 0.79 | NPSR1 (0.53) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL9296706 | 0.76 | NPSR1 (0.50) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL3039143 | 0.76 | NPSR1 (0.50) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL26046013 | 0.75 | NPSR1 (0.43) | NPSR1 | |
| SCHEMBL9298115 | 0.75 | NPSR1 (0.49) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL48652 | 0.75 | HRH3 (0.61) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |