Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956236 | 0.88 | MAPK1 (0.40) | NPSR1MAPK1SMN1; SMN2 | |
| SCHEMBL9296950 | 0.86 | NPSR1 (0.70) | NPSR1HTTCA12CA4CA7 | |
| SCHEMBL3039143 | 0.85 | NPSR1 (0.50) | NPSR1ACACBMTNR1AMTNR1BHTT | |
| SCHEMBL13217212 | 0.83 | NQO2 (0.47) | NPSR1HTTCA12CA9KDM4E | |
| SCHEMBL12342010 | 0.82 | NPSR1 (0.47) | NPSR1ACACBMTNR1AMTNR1BHTT | |
| SCHEMBL17858980 | 0.78 | KCNH2 (0.36) | SMN1; SMN2 | |
| SCHEMBL14562253 | 0.78 | NPSR1 (0.56) | NPSR1MTNR1AMTNR1BHTTCA12 | |
| SCHEMBL17115651 | 0.78 | NPSR1 (0.40) | NPSR1 | |
| SCHEMBL26050179 | 0.77 | CTSS (0.41) | — | |
| SCHEMBL24016455 | 0.76 | NPSR1 (0.54) | NPSR1MTNR1AMTNR1BHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371097-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5364871-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0417751-A2 | New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |