Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.32 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034488 | 0.74 | PDPK1 (0.34) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL25057454 | 0.74 | PDPK1 (0.38) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL12591005 | 0.69 | ADORA2A (0.33) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL21339934 | 0.68 | — | — | |
| SCHEMBL23612485 | 0.67 | XDH (0.33) | — | |
| SCHEMBL25762070 | 0.66 | PDPK1 (0.39) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL21851683 | 0.65 | CYP1A2 (0.50) | YTHDC1YTHDF2 | |
| SCHEMBL1094248 | 0.63 | KDM4E (0.38) | PDPK1YTHDC1YTHDF2 | |
| SCHEMBL17071905 | 0.63 | CCR1 (0.33) | — | |
| SCHEMBL16604729 | 0.62 | ALDH1A1 (0.34) | PDPK1YTHDC1YTHDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225912-A1 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | PLIANT THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |