Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609695 | 1.00 | HSD17B10 (0.46) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL14959019 | 1.00 | HSD17B10 (0.46) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL15088271 | 0.95 | RXFP1 (0.44) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL12176062 | 0.94 | RXFP1 (0.42) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL12176191 | 0.93 | ALDH1A1 (0.43) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL18532606 | 0.93 | ALDH1A1 (0.43) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL12074050 | 0.93 | ALDH1A1 (0.43) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL18790105 | 0.93 | ALDH1A1 (0.43) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL12160772 | 0.92 | HSD17B10 (0.53) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL2591188 | 0.92 | HSD17B10 (0.53) | HSD17B10RXFP1ALDH1A1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508477-B1 | C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2021-11-10 | — | — | EP | disclosed |