SCHEMBL24017232

SCHEMBL24017232

O=C(O)c1cc(OC(F)(F)F)cc(S(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.44
TPX2 Q9ULW0 1/20 0.44
WDR5 P61964 1/20 0.44
KAT6A Q92794 3/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
MRGPRX4 Q96LA9 2/20 0.39
MEP1B Q16820 1/20 0.38
FAAH O00519 1/20 0.38
EPHX2 P34913 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CYP1A2 P05177 1/20 0.37
PPARA Q07869 1/20 0.36
EPAS1 Q99814 1/20 0.36
PIM1 P11309 1/20 0.35
AKR1C3 P42330 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22926045 0.84 AURKA (0.44) AURKATPX2WDR5KAT6ALCK
SCHEMBL11818392 0.84 TSHR (0.43) AURKATPX2WDR5KAT6AMRGPRX4
SCHEMBL18513400 0.83 LCK (0.52) LCKFYNCA1CA2CA7
SCHEMBL732949 0.83 LCK (0.57) WDR5LCKFYNCA1CA2
SCHEMBL23411527 0.82 DDR1 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL29728796 0.82 DDR1 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL23213468 0.82 WDR5 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL29728986 0.82 WDR5 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL475754 0.81 AURKA (0.56) AURKATPX2WDR5KAT6AMRGPRX4
SCHEMBL31550001 0.81 AURKA (0.56) AURKATPX2WDR5KAT6AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996639-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2023-04-21 CN claimed
CN-115996639-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2025-06-13 CN disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 US disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 US disclosed
CN-115996639-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2023-04-21 CN disclosed
WO-2021224323-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES CYP4F3, CYP4X1, GLRX3 AURKA 4197/4885TPX2 122/4885WDR5 847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.