SCHEMBL22926045

SCHEMBL22926045

CS(=O)(=O)c1cc(OC(F)(F)F)cc(C(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.44
TPX2 Q9ULW0 1/20 0.44
WDR5 P61964 1/20 0.44
GPBAR1 Q8TDU6 1/20 0.44
KAT6A Q92794 2/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
PPARA Q07869 1/20 0.39
MRGPRX4 Q96LA9 2/20 0.39
MEP1B Q16820 1/20 0.38
PTGS2 P35354 4/20 0.38
FAAH O00519 1/20 0.38
EPHX2 P34913 1/20 0.38
CYP1A2 P05177 1/20 0.37
PTGS1 P23219 3/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263022 0.87 TSHR (0.42) AURKATPX2WDR5GPBAR1LCK
SCHEMBL29283331 0.87 TSHR (0.42) AURKATPX2WDR5GPBAR1LCK
SCHEMBL31401431 0.86 GPBAR1 (0.45) GPBAR1KAT6AMRGPRX4PTGS2LMNA
SCHEMBL30714944 0.86 GPBAR1 (0.43) GPBAR1KAT6APTGS2LMNASMN1; SMN2
SCHEMBL23411527 0.85 DDR1 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL29728796 0.85 DDR1 (0.43) AURKATPX2WDR5KAT6ALCK
SCHEMBL24017232 0.84 AURKA (0.44) AURKATPX2WDR5KAT6ALCK
SCHEMBL23411542 0.84 WDR5 (0.42) AURKATPX2WDR5KAT6ALCK
SCHEMBL29728801 0.84 WDR5 (0.42) AURKATPX2WDR5KAT6ALCK
SCHEMBL23213468 0.82 WDR5 (0.43) AURKATPX2WDR5KAT6ALCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761402-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-07-15 CN claimed
EP-4739682-A1 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS Janssen Pharmaceutica NV (BE) 2026-05-13 EP disclosed
CN-115996639-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2025-06-13 CN disclosed
WO-2025008058-A1 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS JANSSEN PHARMACEUTICA NV (BE) 2025-01-09 WO disclosed
CN-114867529-B Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-09-27 CN disclosed
CN-118561817-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-30 CN disclosed
CN-118496198-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-08-16 CN disclosed
CN-114502545-B Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-28 CN disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 US disclosed
CN-115996639-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2023-04-21 CN disclosed
US-20230065953-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
US-20230028441-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-01-26 US disclosed
CN-114867529-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2022-08-05 CN disclosed
CN-114761402-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-07-15 CN disclosed
CN-114502545-A Novel heteroaryl-triazole compounds as pesticides 拜耳公司 2022-05-13 CN disclosed
WO-2021224323-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-11-11 WO disclosed
WO-2021105091-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-06-03 WO disclosed
WO-2021069567-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO disclosed
WO-2021013720-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065953-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES GLRX3, TARS2, CYP4F3 AURKA 4266/4885TPX2 127/4885WDR5 706/4885
US-20230348432-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES CYP4F3, CYP4X1, GLRX3 AURKA 4197/4885TPX2 122/4885WDR5 847/4885
US-20230028441-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES PRXL2A, GLRX3, CYP4F3 AURKA 3612/4885TPX2 113/4885WDR5 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.