Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24018384 | 0.85 | IDO1 (0.59) | IDO1KCNH2MEN1KMT2ANPC1 | |
| SCHEMBL24018056 | 0.85 | IDO1 (0.59) | IDO1KCNH2MEN1KMT2ANPC1 | |
| SCHEMBL12783210 | 0.79 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL16616771 | 0.78 | EGLN1 (0.53) | IDO1KCNH2MEN1KMT2ANPC1 | |
| SCHEMBL24018349 | 0.74 | IDO1 (0.61) | IDO1KCNH2MEN1KMT2AEGLN1 | |
| SCHEMBL13753432 | 0.73 | MEN1 (0.63) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL21210731 | 0.71 | MEN1 (0.73) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL20910233 | 0.70 | EGLN1 (0.50) | MEN1KMT2APRSS1CTSGCTRB1 | |
| SCHEMBL24568378 | 0.70 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AXDH | |
| SCHEMBL28182531 | 0.69 | NPC1 (0.97) | KMT2ANPC1RAB9AEGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173145-B2 | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173145-B2 | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase | TPH2, TPH1, IDO2 | IDO1 4/4885KCNH2 2183/4885MEN1 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.