Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.45 |
| ▸ | HTR2B | P41595 | 8/20 | 0.45 |
| ▸ | HTR2A | P28223 | 7/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892191 | 0.84 | HTR2C (0.42) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL28892913 | 0.84 | HTR2C (0.39) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL20472458 | 0.81 | HTR2C (0.45) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL29786449 | 0.81 | HTR2C (0.45) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL22957909 | 0.80 | KDM4E (0.38) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL22957908 | 0.77 | PDE4A (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL22370975 | 0.77 | HTR2C (0.38) | HTR2CHTR2BHTR2A | |
| SCHEMBL30468374 | 0.77 | HTR2C (0.38) | HTR2CHTR2BHTR2A | |
| SCHEMBL13696495 | 0.77 | RIPK1 (0.41) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL26770363 | 0.77 | HTR2C (0.47) | HTR2CHTR2BHTR2ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580220-B1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |