Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892191 | 0.84 | HTR2C (0.42) | HTR2CHTR2BHTR2AFFAR4RIPK1 | |
| SCHEMBL24018822 | 0.84 | HTR2C (0.45) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL22957909 | 0.80 | KDM4E (0.38) | HTR2CHTR2BHTR2ARIPK1PDE4A | |
| SCHEMBL28892422 | 0.78 | L3MBTL1 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22957908 | 0.77 | PDE4A (0.41) | HTR2CHTR2BHTR2APDE4APDE4B | |
| SCHEMBL24716989 | 0.77 | SLC6A2 (0.37) | HTR2CHTR2BHTR2AFFAR4 | |
| SCHEMBL13696495 | 0.77 | RIPK1 (0.41) | HTR2CHTR2BHTR2AKCNN4RIPK1 | |
| SCHEMBL26770363 | 0.77 | HTR2C (0.47) | HTR2CHTR2BHTR2ARIPK1PDE4A | |
| SCHEMBL4678272 | 0.75 | PARP10 (0.46) | FFAR4 | |
| SCHEMBL1390774 | 0.74 | PPARD (0.46) | HTR2CHTR2BHTR2AFFAR4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |